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Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu syndrome): update of September 24, 2026

What's new and why it matters

  1. A study found that blood markers in patients with HHT may change during treatment, possibly indicating how well treatments are working (1). Based on: 1
  2. A review discussed current diagnosis and treatment methods for HHT, highlighting new therapies that could help manage bleeding (2). Based on: 2
  3. Research created a genetic model to help identify patients at high risk for brain arteriovenous malformations (AVMs), which could improve screening approaches (4). Based on: 4
  4. A rare case report described a pregnant woman who had a rupture of a pulmonary arteriovenous malformation, emphasizing the need for quick diagnosis and care (5). Based on: 5

Materials in this update

  1. Circulating angiogenic and inflammatory biomarkers profiling in patients with hereditary hemorrhagic telangiectasia.
    PubMed

    Sep 23, 2026

    This study looked at blood markers in HHT patients during treatment and found some changes related to treatment response.

  2. Current Paradigm Shift in the Treatment of Hereditary Hemorrhagic Telangiectasia: A Narrative Review.
    PubMed

    Sep 23, 2026

    This review discusses current ways to diagnose and treat HHT, focusing on new therapies that may help patients manage bleeding.

  3. Perioperative outcomes and risk stratification following pediatric arteriovenous malformation resection: an ACS NSQIP-P database analysis.
    PubMed

    Sep 23, 2026

    This study examined postoperative outcomes in children after AVM surgeries, finding that some factors increase the risk of complications.

  4. Toward Population-Level Brain AVM Screening: Construction and Evaluation of a Two-Step Genetic Risk Model Incorporating Rare Mendelian Variants and a Novel Polygenic Risk Score.
    PubMed

    Sep 14, 2026

    This research created a two-step genetic model to better identify patients at high risk for brain AVMs, potentially improving screening.

  5. Ruptured pulmonary arteriovenous malformation causing hemothorax during pregnancy: a case report.
    PubMed

    Aug 25, 2026

    This case report highlights a rare instance where a pregnant woman experienced a PAVM rupture, stressing the importance of quick diagnosis and treatment.

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